Alpha Diagnostic International, Inc. Human Neurotensin receptor 1 (NTR1) Control/blocking peptide # 2 NTR12-P

Human Neurotensin receptor 1 (NTR1) Control/blocking peptide # 2 General Information NTR1/NTRH/NTSR1/NT1 (mouse/rat 424 aa; human 418 aa, chromosome 20q1; ~84% interspecies sequence homology) is the levocabastine-insens itive, high affinity receptor for NT. It has the typical structure of GPCR: 7 TM domains with extracellular N-terminus a SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Human Form Antigen/blocking Peptide Antigen 18-aa peptide of Human NTR1; (Gene Accession #P30989) Designated (NTR12-P or control peptide or blocking peptide) conjugated to KLH; Epitope location~ C-terminal, Cytoplasmic domain SpCrossreactivity The human NTR12-P sequence 72% conserved in rat and mouse NTR1. No significant sequence homology exist with other NTR2 or NTR3 or other GPCR. Antibody cross-reactivity in various species has not been studied For research use only, not for diagnostic or therapeutic use.