Alpha Diagnostic International, Inc. Anti-Rat Natural Resistance-Associated Protein 2 (DMT1/NRAMP2, with/without IRE) antiserum #4 NRAMP24-S

Anti-Rat Natural Resistance-Associate d Protein 2 (DMT1/NRAMP2, with/without IRE) antiserum #4 General Information Natural resistance to infection with unrelated intracellular parasite such as Mycobacteria, Salmonella, and Leishmania is controlled by a single gene that encodes a macrophage-specific membrane protein designated as Natural Resistance-Associate d Macrophag SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Rat SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Antiserum Unpurified SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen A 19-aa peptide of rat NRAMP2 (protein accession #, refs 1) ; Designated (NRAMP24 -P or control peptide) conjugated to KLH; Epitope ~Epitope location~ Cytoplasmic domain #4 SpCrossreactivity The rat NRAMP24-P control peptide sequence is 100% conserved in mouse, 94% in human, 73% in zebra fish NRAMP2. This sequence is common in NRAMP2 with or without IRE isoforms. This antibody will not distinguish between these isoforms. Antibody cross-reactivity in various species has not been established For research use only, not for diagnostic or therapeutic use.