Alpha Diagnostic International, Inc. Rat Natural Resistance-Associated Protein 2 (DMT1/NRAMP2, without IRE) Control/blocking peptide #3 NRAMP23-P

Rat Natural Resistance-Associate d Protein 2 (DMT1/NRAMP2, without IRE) Control/blocking peptide #3 General Information Natural resistance to infection with unrelated intracellular parasite such as Mycobacteria, Salmonella, and Leishmania is controlled by a single gene that encodes a macrophage-specific membrane protein designated as Natural Resistance-Associate d Macrophag SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Rat Form Antigen/blocking Peptide Antigen A 22 AA Peptide (designated NRAMP23-P; control peptide) sequence located at the predicted cytoplasmic loop near the C-terminus of rat NRAMP2, without IRE SpCrossreactivity The NRAMP23-P control peptide sequence is 81% conserved in human, mouse, and 77% in monkey NRAMP2 without IRE. This sequence is absent in NRAMP2 with IRE. No significant sequence homology exist with NRAMP1. Antibody cross-reactivity in various species has not been established For research use only, not for diagnostic or therapeutic use.