Alpha Diagnostic International, Inc. Human Natural Resistance-Associated Protein 2 (DMT1/NRAMP2, with IRE) Control/blocking peptide #2 NRAMP22-P

Human Natural Resistance-Associate d Protein 2 (DMT1/NRAMP2, with IRE) Control/blocking peptide #2 General Information Natural resistance to infection with unrelated intracellular parasite such as Mycobacteria, Salmonella, and Leishmania is controlled by a single gene that encodes a macrophage-specific membrane protein designated as Natural Resistance-Associate d Macrophag SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Human Form Antigen/blocking Peptide Antigen 17-aa peptide from human RELM-alpha (1); Designation (#NRAMP22-P, control/blocking peptide) conjugated to KLH; Epitope location~ C-terminal, Cytoplasmic domain SpCrossreactivity The human NRAMP22-P control peptide sequence is 88% conserved in monkey NRAMP2 with IRE. This sequence is absent in NRAMP2 without IRE. No significant sequence homology exist with NRAMP1 or NRAMP2 from mouse or rat.. Antibody cross-reactivity in various species has not been established For research use only, not for diagnostic or therapeutic use.