Alpha Diagnostic International, Inc. Anti-Human Natural Resistance-Associated Protein 2 (DMT1/NRAMP2, with IRE) IgG #2, aff. Pure NRAMP22-A

Anti-Human Natural Resistance-Associate d Protein 2 (DMT1/NRAMP2, with IRE) IgG #2, aff. Pure General Information Natural resistance to infection with unrelated intracellular parasite such as Mycobacteria, Salmonella, and Leishmania is controlled by a single gene that encodes a macrophage-specific membrane protein designated as Natural Resistance-Associate d Macrophag SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Human SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Affinity purified IgG SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 17-aa peptide from human RELM-alpha (1); Designation (#NRAMP22-P, control/blocking peptide) conjugated to KLH; Epitope location~ C-terminal, Cytoplasmic domain SpCrossreactivity The human NRAMP22-P control peptide sequence is 88% conserved in monkey NRAMP2 with IRE. This sequence is absent in NRAMP2 without IRE. No significant sequence homology exist with NRAMP1 or NRAMP2 from mouse or rat.. Antibody cross-reactivity in various species has not been established For research use only, not for diagnostic or therapeutic use.