Alpha Diagnostic International, Inc. Rat Natural Resistance-Associated Protein 2 (DMT1/NRAMP2, with IRE) Control/blocking peptide #1 NRAMP21-P

Rat Natural Resistance-Associate d Protein 2 (DMT1/NRAMP2, with IRE) Control/blocking peptide #1 General Information Natural resistance to infection with unrelated intracellular parasite such as Mycobacteria, Salmonella, and Leishmania is controlled by a single gene that encodes a macrophage-specific membrane protein designated as Natural Resistance-Associate d Macrophag SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Rat Form Antigen/blocking Peptide Antigen 17-aa peptide from rat NRAMP2 (gene accession # O54902, refs 1); Designation (# NRAMP21-P, control/blocking peptide) conjugated to KLH; Epitope location~ C-terminal, Cytoplasmic domain SpCrossreactivity Rat NRAMP21-P control peptide sequence is 100% conserved in mouse NRAMP2 with IRE. This sequence is absent in NRAMP2 without IRE. No significant sequence homology exist with NRAMP1. Antibody cross-reactivity in various species has not been established. For research use only, not for diagnostic or therapeutic use.