Alpha Diagnostic International, Inc. Anti-Human Natural Resistance -Associated Protein 1 (NRAMP-1) antiserum #1 NRAMP11-S

Anti-Human Natural Resistance -Associated Protein 1 (NRAMP-1) antiserum #1 General Information Natural resistance to infection with unrelated intracellular parasite such as Mycobacteria, Salmonella, and Leishmania is controlled by a single gene that encodes a macrophage-specific membrane protein designated as Natural Resistance-Associate d Macrophag SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Human SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Antiserum Unpurified SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 17-aa peptide from human NRAMP1 (1); Designation ( NRAMP11-P, control/blocking peptide) conjugated to KLH; epitope location ~C-terminus, extracellular domain SpCrossreactivity The 17 AA human NRAMP11-P control peptide sequence is 100% conserved in red deer, sheep, 93% in bovine, water buffalo, bison, and 76% in mouse NRAMP1. No significant sequence homology exist with NRAMP2. Antibody cross-reactivity in various species has not been studied For research use only, not for diagnostic or therapeutic use.