Alpha Diagnostic International, Inc. Human Natural Resistance -Associated Protein 1 (NRAMP-1) Control/blocking peptide #1 NRAMP11-P

Human Natural Resistance -Associated Protein 1 (NRAMP-1) Control/blocking peptide #1 General Information Natural resistance to infection with unrelated intracellular parasite such as Mycobacteria, Salmonella, and Leishmania is controlled by a single gene that encodes a macrophage-specific membrane protein designated as Natural Resistance-Associate d Macrophag SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Human Form Antigen/blocking Peptide Antigen 17-aa peptide from human NRAMP1 (1); Designation ( NRAMP11-P, control/blocking peptide) conjugated to KLH; epitope location ~C-terminus, extracellular domain SpCrossreactivity The 17 AA human NRAMP11-P control peptide sequence is 100% conserved in red deer, sheep, 93% in bovine, water buffalo, bison, and 76% in mouse NRAMP1. No significant sequence homology exist with NRAMP2. Antibody cross-reactivity in various species has not been studied For research use only, not for diagnostic or therapeutic use.