Alpha Diagnostic International, Inc. Human NaPi-2/NPT2a Control/blocking peptide (CT) #8 NPT28-P

Human NaPi-2/NPT2a Control/blocking peptide (CT) #8 General Information Inorganic phosphate (Pi) levels are hormonally regulated that affects the physiological activity of bone, kidney, and small intestine. Majority of the Pi is absorbed in the small intestine and reabsorbed in the proximal tubules in the kidney. At least 4 SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Human Form Antigen/blocking Peptide Antigen Human Type-IIa, NPT2/Napi-3 is ~640 aa (chromosome 8) and mouse and rat 637 aa proteins. A 21 AA synthetic peptide (designated NPT28-P; control peptide) within the putative, cytoplasmic, C-terminus of Human NPT2a was synthesized, conjugated to KLH SpCrossreactivity The NPT28-P peptide is 100% conserved in human, rat, mouse, rabbit, and 86% in ovine, 81% bovine, and 71% in opossum NPT2a. No significant sequence homology of NPT25-P is observed with NPT2b or other Pi-transporters (Type-I, III, or IV) transporters. Antibody crossreactivity in various species or isoform is not established For research use only, not for diagnostic or therapeutic use.