Alpha Diagnostic International, Inc. Human NaPi-1/NPT1 Control/blocking peptide #2 NPT12-P

Human NaPi-1/NPT1 Control/blocking peptide #2 General Information Inorganic phosphate (Pi) levels are hormonally regulated that affects the physiological activity of bone, kidney, and small intestine. Majority of the Pi is absorbed in the small intestine and reabsorbed in the proximal tubules in the kidney. At least 4 SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Human Form Antigen/blocking Peptide Antigen Human NPT1 is 465/467aa (chromosome 6) and mouse and rat 465 aa proteins. A 14 AA synthetic peptide (designated NPT12-P; control peptide) within the cytoplasmic, N-terminus of Human NPT1/NaPi-4 was synthesized, conjugated to KLH SpCrossreactivity The NPT12-P peptide is 78% conserved in rat and 71% in mouse Npt1. No significant sequence homology of NPT12-P is observed with other Pi-transporters (Type-II-IV) transporters. Antibody crossreactivity in various species is not established For research use only, not for diagnostic or therapeutic use.