Alpha Diagnostic International, Inc. Rat Nephrin Control/blocking peptide #1 NPHN11-P

Rat Nephrin Control/blocking peptide #1 General Information The mutated NPHS1 gene in congenital nephrotic syndrome of Finnish type, a human disease that leads to massive proteinuria in utero and nephrosis at birth. Nephrin is a transmembrane protein of immunoglobulin super family with 8 Ig like domains, identifie SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Rat Form Antigen/blocking Peptide Antigen 20-aa peptide from Rat NPHN1; Designation (NPHN11-P, control peptide) conjugated to KLH epitope location ~ C-terminus, Intracellular domain SpCrossreactivity The Rat NPHN1 1 control peptide is 81% conserved in human and mouse. No significant sequence homology is seen with other related family members Antibody cross-reactivity in various species has not been studied For research use only, not for diagnostic or therapeutic use.