Alpha Diagnostic International, Inc. Anti-Human Neurite outgrowth inhibitor (Nogo A-C) IgG #2, aff. pure NogoA12-A

Anti-Human Neurite outgrowth inhibitor (Nogo A-C) IgG #2, aff. pure General Information Many tissues such as muscle, skin, liver, and peripheral nerve, have remarkable ability to repair and regrow after injury. However, the CNS (brain and spinal cord) is limited in its ability to repair or regrowth causing permanent brain damage or paralyse SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Human SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Affinity purified IgG SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 13-aa peptide from human Nogo-A (1); Designation (#NOGOA12-P, control/blocking peptide) conjugated to KLH; epitope location ~ between the putative 2nd-3rd transmembrane domain SpCrossreactivity The human NogoA12-P peptide sequence is conserved in all 3 isoforms (human Nogo A-C). It is 92% identical in mouse, rat Nogo or rat foocen-m1/2 protein and 100% in monkey Nogo-A. NogoA12-P is within the 25-aa region identified for the inhibition of neurite outgrowth (1). Antibody crossreactivity of NogoA12 in various species is not established For research use only, not for diagnostic or therapeutic use.