Alpha Diagnostic International, Inc. Mouse Neuromedin U control/blocking peptide # 4 NMU71-P

Mouse Neuromedin U control/blocking peptide # 4 General Information NmU is synthesized from a large precursor peptide and cleaved into 25-aa (human NmU, 25 aa; rat NmU, 23 aa; porcine NmU, 25 aa) and 8-aa (Nmu-8; 18-25) biologically active peptides. NMU peptides from various species share the greatest homology in the the SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Mouse Form Antigen/blocking Peptide Antigen Three peptides designated as NMUR51-P from rat, NMU61-P from human, and NMU71-P from mouse NmU (1) within N-terminal domain were used for antibody production. The three peptides (designated at NMU41-P, control peptides) conjugated to KLH SpCrossreactivity The 14-aa mouse NMU71-P control peptide shares no significant sequence homology with rat or human or NmU from other species. Therefore, affinity pure mouse NMU71-A antibody has no appreciable crossreactivity with rat or human NmU. We suggest the use of Cat # NMU51-A for rat and Cat # NMU61-A for human NmU. Antibody cross-reactivity in various other species has not been studied For research use only, not for diagnostic or therapeutic use.