Alpha Diagnostic International, Inc. Human Neuromedin U control/blocking peptide # 3 NMU61-P

Human Neuromedin U control/blocking peptide # 3 General Information NmU is synthesized from a large precursor peptide and cleaved into 25-aa (human NmU, 25 aa; rat NmU, 23 aa; porcine NmU, 25 aa) and 8-aa (Nmu-8; 18-25) biologically active peptides. NMU peptides from various species share the greatest homology in the the SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Human Form Antigen/blocking Peptide Antigen Three peptides designated as NMUR51-P from rat, NMU61-P from human, and NMU71-P from mouse NmU (1) within N-terminal domain were used for antibody production. The three peptides (designated at NMU41-P, control peptides) were coupled to KLH SpCrossreactivity The 14-aa human NMU61-P control peptide shares no significant sequence homology with rat or mouse or NmU from other species. Therefore, affinity pure human NMU61-A antibody has no appreciable crossreactivity with mouse or rat NmU. We suggest the use of Cat # NMU51-A for rat and Cat # NMU71-A for mouse NmU. Antibody cross-reactivity in various other species has not been studied For research use only, not for diagnostic or therapeutic use.