Alpha Diagnostic International, Inc. Anti-Human Nicastrin IgG #1, aff. pure NICN11-A

Anti-Human Nicastrin IgG #1, aff. pure General Information Human nicastrin gene (chromosome 1) encodes a transmembrane protein of 709 aa (mouse 708 aa). It has a putative signal peptide; a long N-terminal hydrophilic domain containing glycosylation, N-myristoylation and phosphorylation motifs; a 20-residue hydr SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Human SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Affinity purified IgG SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 19-aa peptide from human nicastrin- (1); Designation (#NICN11-P, control or blocking peptide) conjugated to KLH; Epitope location~ C-terminal, Cytoplasmic domain SpCrossreactivity Human NICN11-P antigenic sequence is 94% conserved in mouse and rat. However, no significantly sequence homology was detected with the C. elegans or drosophila protein. Antibody crossreactivity in various species is not established For research use only, not for diagnostic or therapeutic use.