Alpha Diagnostic International, Inc. Rat Na-H Exchanger 1 (NHE1) Control/blocking peptide # 2 NHE12-P

Rat Na-H Exchanger 1 (NHE1) Control/blocking peptide # 2 General Information NHE1 (rat/mouse; 820 aa; human 815 aa; chromosome 1 p35-36.1) is 'House Keeper' and is expressed ubiquitously in all tissues. It is implicated in pH homeostasis, volume regulation, and probably cell proliferation. It is expressed on basolateral surface SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Rat Form Antigen/blocking Peptide Antigen 22aa peptide of Rat NHE1 ; (gene accession #P26431) Designated (NHE11-P or control peptide). conjugated to KLH; Epitope location~ C-terminal, Cytoplasmic domain SpCrossreactivity The 22-aa NHE11-P sequence shows 100% homology with human, mouse, rat, bovine, pig and rabbit , and 90% with the hamster NHE1. No significant sequence homology exist with other NHE isoforms (NHE2-5). Antibody crossreactivity in various species is not established For research use only, not for diagnostic or therapeutic use.