Alpha Diagnostic International, Inc. Anti-Human Nogo Receptor (Ngr) antiserum NGR11-S

Anti-Human Nogo Receptor (Ngr) antiserum General Information Recently, a brain specific leucine-rich-repeat protein with high affinity for soluble Nogo-66, termed Nogo receptor (Ngr) has been cloned and characterized. Cleavage of Ngr from the axonal surface renders neurons insensitive to Nogo-66. Ngr expression i SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Human SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Antiserum Unpurified SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen A 17-aa peptide (designated NGR11-P control peptides) within the C-terminus of human Ngr (1) was synthesized, conjugated to KLH SpCrossreactivity The human NGR11-P peptide sequence is 100% conserved in human, mouse, rat, and monkey Ngr. No significant sequence homology of NGR11-P is detected with Rtn family members. Antibody crossreactivity in various species is not established. For research use only, not for diagnostic or therapeutic use.