Alpha Diagnostic International, Inc. Anti-Mouse Neprilysin-beta (NEPL-beta) IgG (aff pure) NEPLB21-A

Anti-Mouse Neprilysin-beta (NEPL-beta) IgG (aff pure) General Information NEPL- (variously called SEP/NL1/NEPII) is type II transmembrane enzyme containing a single polypeptide chain of 765aa (~110 KDa) with cytosolic and transmembrane domains and a large extracellular C-terminal core containing the peptidase active site. The SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Mouse SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Affinity purified IgG SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen A 13-aa peptide sequence (gene accession #NP038811.1) (designated NEPLB21-P or control peptide), mapping near the extracellular N-terminus (within the unique 23-aa insert) of mouse neprilysin-like protease- (NEPL-beta) (1) coupled to KLH SpCrossreactivity Mouse NEPLB21-P antigenic/control peptide sequence is 76% conserved in rat NEPL- No significant sequence homology of NEPLB21-P is seen with NEP or other NEPLs. Antibody reactivity in various species is not known. For research use only, not for diagnostic or therapeutic use.