Alpha Diagnostic International, Inc. Anti-Mouse Neprilysin-alpha (NEPL-alpha) antiserum NEPLA11-S

Anti-Mouse Neprilysin-alpha (NEPL-alpha) antiserum General Information NEPL- (variously called SEP /splice 1) is a type II trans-membrane metallopeptidase (~100 kDa non-glycosylated and 120 kDa glycosylated) containing a highly glycosylated polypeptide chain of 742aa with a HEXXH zinc-binding consensus, cytoplasmic tail and SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Mouse SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Antiserum Unpurified SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 17-aa peptide from (gene accession # NP038811.1) mouse neprilysin-like protease-a (NEPL-a) ( NEPLA11-P, control/blocking peptide) conjugated to KLH; epitope location ~ N-terminal, Cytoplasmic domain SpCrossreactivity The NEPLA11-P antigenic/control peptide is 100% conserved in mouse NEPL- and . No significant sequence homology of NEPLA11-P is seen with other proteins. Antibody reactivity in various species is not known For research use only, not for diagnostic or therapeutic use.