Alpha Diagnostic International, Inc. Mouse Neprilysin-alpha (NEPL-alpha) Control/blocking peptide NEPLA11-P

Mouse Neprilysin-alpha (NEPL-alpha) Control/blocking peptide General Information NEPL- (variously called SEP /splice 1) is a type II trans-membrane metallopeptidase (~100 kDa non-glycosylated and 120 kDa glycosylated) containing a highly glycosylated polypeptide chain of 742aa with a HEXXH zinc-binding consensus, cytoplasmic tail and SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Mouse Form Antigen/blocking Peptide Antigen 17-aa peptide from (gene accession # NP038811.1) mouse neprilysin-like protease-a (NEPL-a) ( NEPLA11-P, control/blocking peptide) conjugated to KLH; epitope location ~ N-terminal, Cytoplasmic domain SpCrossreactivity The NEPLA11-P antigenic/control peptide is 100% conserved in mouse NEPL- and . No significant sequence homology of NEPLA11-P is seen with other proteins. Antibody reactivity in various species is not known For research use only, not for diagnostic or therapeutic use.