Alpha Diagnostic International, Inc. Rat Nephrin related protein 2 (NEPH2) Control/blocking peptide #1 NEPH21-P

Rat Nephrin related protein 2 (NEPH2) Control/blocking peptide #1 General Information NEPH2 ( Human 778aa, chrm 11q24) has no N-terminal signal peptide; the C-terminus will be inside and do have transmembrane region. It has the common domain architecture of 5 Ig domains. NEPH2 id present in brain, heart, kidney and nervous system. At leas SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Rat Form Antigen/blocking Peptide Antigen 14-aa peptide 727-740 aa from Rat NEPH2/KIRRE (protein accession # Q09GS6, refs 1) Designation (NEPH21-P, control peptide); Epitope location~ C-terminal, Cytoplasmic domain SpCrossreactivity The Rat NEPH21-P Control/blocking peptide is 100% conserved in human and mouse NEPH2/KIRR3. Based upon the sequences of various NEPH2 isoforms, the epitope of NEPH21-P is found in isoforms 1-2, and 4. No significant sequence homology is seen with other related family members Antibody cross-reactivity in various species has not been studied For research use only, not for diagnostic or therapeutic use.