Alpha Diagnostic International, Inc. Anti-Rat Nephrin related protein 2 (NEPH2) IgG #1, aff pure NEPH21-A

Anti-Rat Nephrin related protein 2 (NEPH2) IgG #1, aff pure General Information NEPH2 ( Human 778aa, chrm 11q24) has no N-terminal signal peptide; the C-terminus will be inside and do have transmembrane region. It has the common domain architecture of 5 Ig domains. NEPH2 id present in brain, heart, kidney and nervous system. At leas SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Rat SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Affinity purified IgG SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 14-aa peptide 727-740 aa from Rat NEPH2/KIRRE (protein accession # Q09GS6, refs 1) Designation (NEPH21-P, control peptide); Epitope location~ C-terminal, Cytoplasmic domain SpCrossreactivity The Rat NEPH21-P Control/blocking peptide is 100% conserved in human and mouse NEPH2/KIRR3. Based upon the sequences of various NEPH2 isoforms, the epitope of NEPH21-P is found in isoforms 1-2, and 4. No significant sequence homology is seen with other related family members Antibody cross-reactivity in various species has not been studied For research use only, not for diagnostic or therapeutic use.