Alpha Diagnostic International, Inc. Anti-Rat Na-Ca Exchanger 1 (NCX1) IgG #2, aff pure NCX12-A

Anti-Rat Na-Ca Exchanger 1 (NCX1) IgG #2, aff pure General Information NCX1 (rat 971 aa, human 970 aa, mouse 970 aa) is most prominently expressed in the heart where it plays a major role in excitation-contracti on coupling, but is also present in most other tissues. Alternative spicing of NCX1/NACA1 produces numerous tissue SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Rat SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Affinity purified IgG SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 23-aa peptide of Rat (gene accession # S32345) NCX1 ; Designated (NCX12-P or control peptide pr blocking peptide) conjugated to KLH; epitope location ~ N-terminal, Cytoplasmic domain SpCrossreactivity The 23 AA rat NCX12-P control peptide 100% conserved in mouse, dog, cat, 95% in human, rabbit, monkey, bovine, 86% in chicken, and 73% in frog NCX1. NCX11-P epitope is conserved in NCX isoforms 1-7 that have deletions or substitutions after ~600 aa. No significant sequence homology is detected with other NCX. Antibody cross-reactivity in various species has not been studied For research use only, not for diagnostic or therapeutic use.