Alpha Diagnostic International, Inc. Anti-Rat Na-Bicarbonate Transporter 1 (NBC1) IgG #1, aff. Pure NBC11-A

Anti-Rat Na-Bicarbonate Transporter 1 (NBC1) IgG #1, aff. Pure General Information NBC1 (human, rat, mouse 1035 aa, also called NBC-1A/1B, hkNBC, rkNBC, pNBC, hhNBC, SLC4A4) was initially cloned from human Kidney. NBC1 is 30-35% identical with AEs. It is strongly expressed in the kidney and pancreas. The rat kidney NBC1 (rkNBC1; 1035 SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Rat SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Affinity purified IgG SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen A 20-aa peptide of rat NBC1 (protein accession #, refs 1) ; Designated (NBC11-P or control peptide) conjugated to KLH; epitope location ~ N-terminal, Cytoplasmic domain SpCrossreactivity Rat NBC11-P sequence is 100% conserved in mouse, rat, human, and rabbit NBC1/PSLC4A4/kNBC, and 75% in frog NBC1. This region is also shared 100% with pNBC/ PSLC4A5. Therefore, antibodies will recognize both the kidney and pancreatic/heart isoforms. No significant sequence homology of NBC11-P was found with NBC2 or NBC3. Antibody crossreactivity in various species is not established For research use only, not for diagnostic or therapeutic use.