Alpha Diagnostic International, Inc. Mouse beta-Defensin 1 control/blocking peptide #1 MBD11-P

Mouse beta-Defensin 1 control/blocking peptide #1 General Information The genes encoding human a and ß -defensins are clustered in a contiguous segment of chromosome 8p23. Defensins are classified into two families designated a ? and ß - based on distinctive, although similar, tri-disulfide linkages in the peptides. -de SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Mouse Form Antigen/blocking Peptide Antigen Mouse MBD-1 is synthesized from 69 aa precursor (mature peptide 33-69 aa). A 16 AA Peptide (designated #MBD11-P; control peptide) Epitope location ~ N-terminus of mature MBD-1 conjugated to KLH SpCrossreactivity The MBD11-P control peptide is 87% conserved in rat MBD-1. No significant homology exists with human beta-defensin 1 or other defensins. We recommend the use of antibody cat # HBD12 for the detection of human BD-1. Antibody cross-reactivity in various species has not been studied For research use only, not for diagnostic or therapeutic use.