Alpha Diagnostic International, Inc. Anti-Mouse beta-Defensin 1, IgG #1, aff pure MBD11-A

Anti-Mouse beta-Defensin 1, IgG #1, aff pure General Information The genes encoding human a and ß -defensins are clustered in a contiguous segment of chromosome 8p23. Defensins are classified into two families designated a ? and ß - based on distinctive, although similar, tri-disulfide linkages in the peptides. -de SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Mouse SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Affinity purified IgG SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen Mouse MBD-1 is synthesized from 69 aa precursor (mature peptide 33-69 aa). A 16 AA Peptide (designated #MBD11-P; control peptide) Epitope location ~ N-terminus of mature MBD-1 conjugated to KLH SpCrossreactivity The MBD11-P control peptide is 87% conserved in rat MBD-1. No significant homology exists with human beta-defensin 1 or other defensins. We recommend the use of antibody cat # HBD12 for the detection of human BD-1. Antibody cross-reactivity in various species has not been studied For research use only, not for diagnostic or therapeutic use.