Alpha Diagnostic International, Inc. Mouse Lipin-1 Control/blocking peptide control/blocking peptide #1 LPN11-P

Mouse Lipin-1 Control/blocking peptide control/blocking peptide #1 General Information Lipin-1: The human and mouse LPIN-1 genes have been mapped at chromosomes 2p21 and 12, respectively. A region (POMC) on this same chromosome also encodes pro-opiomelanocortin , a locus linked to total adiposity and the levels of plasma protein Leptin. The SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Mouse Form Antigen/blocking Peptide Antigen 16-aa peptide of Mouse Lipin-1 (1); Designated (LPN11-P or control peptide/blocking peptide) conjugated to KLH; epitope location ~ within N-terminus SpCrossreactivity Mouse LPN11-P peptide is 93% conserved in rat, 81% in human and Chimp, and 75% in chicken Lipin-1 proteins. The epitope of LPN11-P is around 120-aa region that is well before the truncation site for isoforms-1. Theretofore, LPN11-P epitope is present in both isoforms-1 and 2. No significant sequence homology of LPN11-P is seen with Lipin-2, Lipin-3 or other proteins. Antibody reactivity in various species is not known. For research use only, not for diagnostic or therapeutic use.