Alpha Diagnostic International, Inc. Anti-Mouse Lipin-1 IgG #1, Aff. Pure LPN11-A

Anti-Mouse Lipin-1 IgG #1, Aff. Pure General Information Lipin-1: The human and mouse LPIN-1 genes have been mapped at chromosomes 2p21 and 12, respectively. A region (POMC) on this same chromosome also encodes pro-opiomelanocortin , a locus linked to total adiposity and the levels of plasma protein Leptin. The SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Mouse SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Affinity purified IgG SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 16-aa peptide of Mouse Lipin-1 (1); Designated (LPN11-P or control peptide/blocking peptide) conjugated to KLH; epitope location ~ within N-terminus SpCrossreactivity Mouse LPN11-P peptide is 93% conserved in rat, 81% in human and Chimp, and 75% in chicken Lipin-1 proteins. The epitope of LPN11-P is around 120-aa region that is well before the truncation site for isoforms-1. Theretofore, LPN11-P epitope is present in both isoforms-1 and 2. No significant sequence homology of LPN11-P is seen with Lipin-2, Lipin-3 or other proteins. Antibody reactivity in various species is not known. For research use only, not for diagnostic or therapeutic use.