Alpha Diagnostic International, Inc. Anti-Human/Mouse K-Cl Cotransporter 3 (KCC3) IgG #2, aff pure KCC32-A

Anti-Human/Mouse K-Cl Cotransporter 3 (KCC3) IgG #2, aff pure General Information The K-Cl cotransporters mediate the coupled movement of K+ and Cl- ions across the cell membranes. This transport process is involved in the regulatory volume decrease in response to cell swelling in red cells and vectorial movement of Cl- ions across th SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Human/Mouse SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Affinity purified IgG SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 17-aa peptide of Human KCC3; (Gene Accession #Q924N4) Designated (KCC32-P or control peptide or blocking peptide) conjugated to KLH; Epitope location~ C-terminal, Cytoplasmic domain SpCrossreactivity Human KCC32-P antigenic peptide is conserved 100% mouse and monkey KCC3, and 82% in frog. It is found in both alternatively spliced forms of the human KCC3 (1099 aa) and KCC3a (1150 aa) (refs 1). We have raised another antibody (cat # KCC31-S) using the N-terminal peptide sequence that is found in the short form of hKCC3 (1099aa). KCC32-P has no significant sequence homology with other KCCs or CCC. Antibody crossreactivity in various species is not established For research use only, not for diagnostic or therapeutic use.