Alpha Diagnostic International, Inc. Anti-Rat K-Cl Cotransporter 2 (KCC2) antiserum #1 KCC21-S

Anti-Rat K-Cl Cotransporter 2 (KCC2) antiserum #1 General Information The K-Cl cotransporters mediate the coupled movement of K+ and Cl- ions across the cell membranes. This transport process is involved in the regulatory volume decrease in response to cell swelling in red cells and vectorial movement of Cl- ions across th SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Rat SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Antiserum Unpurified SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 18aa peptide of Rat KCC2 ; (Gene Accession #Q63633, 1116-aa) Designated (KCC21-P or control peptide). conjugated to KLH; epitope location ~ N-terminal, Cytoplasmic domain SpCrossreactivity Rat KCC21-P sequence is 94% conserved in mouse and human. No significant sequence homology is seen with other KCCs or CCC. Antibody cross-reactivity in various species has not been studied. For research use only, not for diagnostic or therapeutic use.