Alpha Diagnostic International, Inc. Anti-Rat/human Iron regulatory protein 2 (IRP-2) antiserum IRP21-S

Anti-Rat/human Iron regulatory protein 2 (IRP-2) antiserum General Information Iron regulatory proteins (IRP-1 and IRP-2) are cytoplasmic mRNA-binding proteins that control intracellular iron levels by regulating the translation of ferritin, Tfrs, and other proteins congaing iron-responsive element (IRE) located at the 5?-UTR. IRP SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Rat/Human SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Antiserum Unpurified SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 20-aa peptide from rat, mouse, and human IRP-2 (1); Designation ( # H1R11-P, control/blocking peptide) conjugated to KLH; epitope location ~ N-terminus SpCrossreactivity The IRP21-P sequence is 100% conserved in mouse, rat, and human IRP-2. No significant sequence homology exist with IRP-1. Antibody cross-reactivity in various species has not been studied For research use only, not for diagnostic or therapeutic use.