Alpha Diagnostic International, Inc. Anti-Rat Heme Oxygenase 1 (HO-2) antiserum #2 HO22-S

Anti-Rat Heme Oxygenase 1 (HO-2) antiserum #2 General Information Heme oxygenase is the rate-limiting microsomal enzyme in the heme degradative pathway. Heme oxygenase catalyzes the NADPH, O2 and cytochrome P450 reductase dependent oxidation of heme to form equimolar biliverdin, carbon monoxide, a putative neurotransmi SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Rat SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Antiserum Unpurified SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 13-aa peptide from rat HO2 (1); Designation (HO22-P, control peptide) coupled to KLH; epitope location ~ N-terminus SpCrossreactivity The Human HO23-P sequence is 100% conserved in mouse, rat, human HO-2. HO23-P is also greatly conserved in HO-1. High sequence conservation is observed in Euryoxic fish, puffer fish. Cyanobacteria, and plant read Alga Heme oxygenases. So this antibody is likely to crossreact with HO-2 and HO-1 from many species. Antibody cross-reactivity in various species has not been studied. For research use only, not for diagnostic or therapeutic use.