Alpha Diagnostic International, Inc. Mouse (mrl/lpr) serum containing autoantibodies to HNE HNE31-M

Mouse (mrl/lpr) serum containing autoantibodies to HNE General Information HNE is a major product of endogenous lipid peroxidation. The w-6-family (linoleic and arachidonic acids) of polyunsaturated fatty acids may produce HNE as a result of free radical attack. HNE is a highly reactive compound and it can react with several f SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2486-seconda ry-antibodies-mouse. htm SpeciesReactivity All species SugNegativeControl Non-immune Rabbit IgG Cat# 20008-1 Form Antiserum Unpurified-Mouse SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen Autoimmune mice (mrl/lpr strain) were screened for the presence for high titered antibodies to HNE by ELISA using purified HNE-ovalbumin coated ELISA plates. Mice showing high titer were pooled SpCrossreactivity Since autoimmune mice contain autoantibodies to other antigens, this antiserum should only be used in an antigen specific assay. The use of these antibodies is not recommended in immunoassays where autoantibodies to dsDNA, ANA and other autoantigens may interfere with the results. For research use only, not for diagnostic or therapeutic use.