Alpha Diagnostic International, Inc. Anti-Human Pro-Hepcidin (Pro-Hepc) IgG # 4, aff pure HEPC14-A

Anti-Human Pro-Hepcidin (Pro-Hepc) IgG # 4, aff pure General Information Hepcidin (Hepc, hepatic bactericidal protein) or LEAP (liver expressed antimicrobial peptide) is small, cysteine-rich peptide, antimicrobial peptide similar to defensins and thionins. Hepcidin (unprocessed, proprotein in mouse 83 aa, rat/human 84 aa) are SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Human SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Affinity purified IgG SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 11-aa peptide from human Pro-HEPC (designated HEPC14-P or control peptide or blocking peptide) conjugated to KLH; epitope location ~ N-terminus (after the signal peptide SpCrossreactivity The human HEPC14-P sequences is 63% conserved in mouse/rat pro-HEPC. This sequence is removed from the mature 20-25 secreted forms of HEPC. So antibodies will not react with the secreted forms of HEPC. Antibody cross-reactivity in various species has not been studied. Full length, human 25-aa (cat # HEPC61-P) and 20-aa HEPC (cat # HEPC71-P) and mouse 25-aa HEPC (cat # HEPC-81) are also available for various studies For research use only, not for diagnostic or therapeutic use.