Alpha Diagnostic International, Inc. Anti-Mouse/Human Hepcidin-25 IgG # 3, aff pure HEPC13-A

Anti-Mouse/Human Hepcidin-25 IgG # 3, aff pure General Information Hepcidin (Hepc, hepatic bactericidal protein) or LEAP (liver expressed antimicrobial peptide) is small, cysteine-rich peptide, antimicrobial peptide similar to defensins and thionins. Hepcidin (unprocessed, proprotein in mouse 83 aa, rat/human 84 aa) are SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Mouse/Human SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Affinity purified IgG SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen A 7-aa peptide sequences from the N-terminus of mature human and mouse 25-aa HEPC were synthesized. The two peptides (designated HEPC13-P or control peptide) conjugated to KLH SpCrossreactivity The mouse HEPC13-P sequences from mouse/rat, and human differ by just aa in 25-aa mature HEPC. The HEPC13-P sequence is truncated by 5-aa in the 20-aa major secreted HEPC. Anti-HEPC13-P do not have significant reactivity with 20-aa HEPC peptide. Anti-HEPC13-P could potentially react with the unprocessed larger 60-aa pro-HEPC if present in the samples or tissues. Antibody cross-reactivity in various species has not been studied. Full length, human 25-aa (cat # HEPC61-P) and 20-aa HEPC (cat # HEPC71-P) and mouse 25-aa HEPC (cat # HEPC-81) are also available for various studies For research use only, not for diagnostic or therapeutic use.