Alpha Diagnostic International, Inc. Anti-Human Hepcidin (20-25 hepc) IgG # 2, aff pure HEPC12-A

Anti-Human Hepcidin (20-25 hepc) IgG # 2, aff pure General Information Hepcidin (Hepc, hepatic bactericidal protein) or LEAP (liver expressed antimicrobial peptide) is small, cysteine-rich peptide, antimicrobial peptide similar to defensins and thionins. Hepcidin (unprocessed, proprotein in mouse 83 aa, rat/human 84 aa) are SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Human SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Affinity purified IgG SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 13-aa peptide from mature human HEPC (1); Designated # HEPC12-P, control/blocking peptide) conjugated to KLH; epitope location ~ C-terminus SpCrossreactivity The Human HEPC12-P sequence is conserved in all 3 human HEPC peptides (20-, 22- and 25-aa C-terminal fragments). Therefore, HEPC12-P antibody will detect all 3 processed forms of human HEPC. It is 69% conserved in mouse, and 61% in rat HEPC. Anti-HEPC12-P could potentially react with the unprocessed larger 60-aa pro-HEPC if present in the samples or tissues. Antibody cross-reactivity in various species has not been studied. We recommend the use of cat # HEPC11-S for the detection of mouse/rat HEPC. Full length, human 25-aa (cat # HEPC61-P) and 20-aa HEPC (cat # HEPC71-P) and mouse 25-aa HEPC (cat # HEPC-81) are also available for various studies For research use only, not for diagnostic or therapeutic use.