Alpha Diagnostic International, Inc. Anti-Mouse Hepcidin (20-25 hepc) antiserum # 1 HEPC11-S

Anti-Mouse Hepcidin (20-25 hepc) antiserum # 1 General Information Hepcidin (Hepc, hepatic bactericidal protein) or LEAP (liver expressed antimicrobial peptide) is small, cysteine-rich peptide, antimicrobial peptide similar to defensins and thionins. Hepcidin (unprocessed, proprotein in mouse 83 aa, rat/human 84 aa) are SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Mouse SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Antiserum Unpurified SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 13-aa peptide of mouse HEPC (1) ; Designated (HEPC11-P or control/blocking peptide). epitope location ~ C-terminus of mature HEPC SpCrossreactivity The mouse HEPC11-P sequence is 92% conserved in rat, 69% in human HEPC (20-, 22- and 25-aa C-terminal fragments). Anti-HEPC11-P could potentially react with the unprocessed larger 60-aa pro-HEPC if present in the samples or tissues. Antibody cross-reactivity in various species has not been studied. We recommend the use of cat # HEPC12-S for the detection of human HEPC. Full length, human 25-aa (cat # HEPC61-P) and 20-aa HEPC (cat # HEPC71-P) and mouse 25-aa HEPC (cat # HEPC-81) are also available for various studies For research use only, not for diagnostic or therapeutic use.