Alpha Diagnostic International, Inc. Human Alpha Defensin 1-3 (NP1-3/hNP1-3)control/blocking peptide #1 HDEFA11-P

Human Alpha Defensin 1-3 (NP1-3/hNP1-3)contro l/blocking peptide #1 General Information Defensins are a large family of broad-spectrum antimicrobial peptides, identified originally in leukocytes of rabbits and humans. Defensins, cationic/polar peptides (30-35 aa; 3-4 kDa), are distinguished by a conserved tri-disulfides and a largely -Shee SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Human Form Antigen/blocking Peptide Antigen Human alpha 1 defensins (HDEFA1) is synthesized from 94 precursor (mature peptide 65-94). A 16-aa peptide (designated HDEFA11-P; control peptides) Epitope location ~ C-terminus of human mature alpha 1 defensin-1 (1) conjugated to KLH SpCrossreactivity The HDEFA11-P control peptides is common to human HNP1-3. The peptide has significant sequence homology with monkey alpha defensins 1-3. No significant homology exists with human alpha-defensins 4-6. The HDEFA11-P control peptide is available for antibody blocking to confirm specificity of antibodies. Antibody cross-reactivity in various species has not been studied. For research use only, not for diagnostic or therapeutic use.