Alpha Diagnostic International, Inc. Anti-Rat Hyperpolarization-activated Cyclic Nucleotide-gated channel 4 (HCN4) IgG, aff pure HCN41-A

Anti-Rat Hyperpolarization-ac tivated Cyclic Nucleotide-gated channel 4 (HCN4) IgG, aff pure General Information HCN4 (rat 1198 aa, human 1203-aa, chromosome 15q24-q25) is highly expressed at heart ventricle and atrium, brain (olfactory bulb, thalamus), and testis. expressed in brain. SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Rat SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Affinity purified IgG SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 15-aa peptide from rat HCN4(1); (Gene Accession #NP067690.1) Designation (#HCN41-P, control/blocking peptide) conjugated to KLH; Epitope location~ C-terminal, Cytoplasmic domain SpCrossreactivity The rat HCN41-P peptide is 100% conserved in mouse, 93% in rabbit and 86% in human or primate HCN4. No significant sequence homology of HCN41-P is seen with other HCNs or any other protein. Antibody reactivity in various species is not known. For research use only, not for diagnostic or therapeutic use.