Alpha Diagnostic International, Inc. Anti-Human Hyperpolarization-activated Cyclic Nucleotide-gated channel 1 (HCN1) antiserum HCN11-S

Anti-Human Hyperpolarization-ac tivated Cyclic Nucleotide-gated channel 1 (HCN1) antiserum General Information HCN1, also known as Brain cyclic nucleotide channel gated 1, BCNG1 or HAC-2 (mouse/rat 910 aa, human 749-aa), is primarily expressed in brain. In mouse, HCN1 is mainly expressed in the neocortex, the CA1 region of the hippocampus, the superior colliculus SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Human/Rat SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Antiserum Unpurified SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 14-aa peptide from (Gene Accession # NP 034538) human/mouse HCN1 (1); Designation (#HCN11-P, control/blocking peptide) conjugated to KLH; Epitope location~ C-terminal, Cytoplasmic domain SpCrossreactivity The HCN11-P peptide is 100% conserved in human, mouse and 92% in rabbit and rat HCN1. No significant sequence homology of HCN11-P is seen with other HCNs or any other protein. Antibody reactivity in various species is not known For research use only, not for diagnostic or therapeutic use.