Alpha Diagnostic International, Inc. Anti-human beta-Defensin 3 (BD-3) IgG #1 aff pure HBD31-A

Anti-human beta-Defensin 3 (BD-3) IgG #1 aff pure General Information The genes encoding human a and ß -defensins are clustered in a contiguous segment of chromosome 8p23. Defensins are classified into two families designated a ? and ß - based on distinctive, although similar, tri-disulfide linkages in the peptides. -def SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Human SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Affinity purified IgG SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 13 aa peptide from mouse MBD-3 (MBD31-P) and 15-aa peptide from HBD-3, HBD31-P (the mixture designated HBD31-P; control peptides) were coupled to KLH. Epitope location ~ N-terminus of mature defensin-3 (1) SpCrossreactivity The HBD31-P and MBD31-P control peptides are specific for human and mouse defensin-3. No significant homology exists with other beta-defensins. The HBD31-P control peptide is available for antibody blocking to confirm specificity of antibodies. It is not suitable for testing by Western due to small size. Antibody cross-reactivity in various species has not been studied For research use only, not for diagnostic or therapeutic use.