Alpha Diagnostic International, Inc. Anti-Human beta-Defensin 2 (BD-2/hBD-2), IgG #1, aff pure HBD21-A

Anti-Human beta-Defensin 2 (BD-2/hBD-2), IgG #1, aff pure General Information Antimicrobial peptides are a common mechanism of host defense utilized by a variety of species, from insects to humans. Defensins are a large family of broad-spectrum antimicrobial peptides, identified originally in leukocytes of rabbits and humans. Defe SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Human SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Affinity purified IgG SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 3 different peptides (14 aa from human BD-2, 14-aa from rat defensin-2, and 17 aa from mouse BD-2 (the mixture designated as designated HBD21-P; control peptides) Epitope location ~ near the N-terminus of mature BD-2 conjugated to KLH SpCrossreactivity The beta-defensin-2 peptides selected for antibody production have no significant sequence homology with other defensins. Antibody HBD21 reacts with HBD-2 from mouse, rat, and human beta defensin-2. Antibody cross-reactivity in various other species has not been studied. For research use only, not for diagnostic or therapeutic use.