Alpha Diagnostic International, Inc. Mouse glucokinase regulatory protein (GKRP/GCKR) control/blocking peptide GKRP11-P

Mouse glucokinase regulatory protein (GKRP/GCKR) control/blocking peptide General Information Hexokinase catalyzes the first step of several metabolic pathways by converting D-hexose to D-hexose-6-P. Hexokinase is an allosteric enzyme inhibited by its products glucose-6-phosphate. At least 4 related hexokinase isoforms (HXKI-III; HXK-IV also kno SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Mouse Form Antigen/blocking Peptide Antigen Mouse GKRP is 587-aa protein. A 16-aa peptide of Mouse GKRP/Gckr (gene accession # Q91X44, refs 1); Designated (GKRP11-P or control peptide) conjugated to KLH. Epitope location ~ C-terminus SpCrossreactivity Mouse GKRP11-P control peptide is 100% conserved in rat, 81% in human/Chimp, and 79% in canine GKRP proteins. No significant homology of GKRP11-P is seen with HXK2-4. Antibody crossreactivity in various species is not known For research use only, not for diagnostic or therapeutic use.