Alpha Diagnostic International, Inc. Rat GABAb-R2 (GBR2) Control/blocking peptide #2 GBR22-P

Rat GABAb-R2 (GBR2) Control/blocking peptide #2 General Information GABA ( -amino butyric acid) is the most abundant neurotransmitter in mammalian brain. GABA exerts its effects through ionotropic ligand-gated GABAA, GABAC and GABAB receptors (GABABRs). Presynaptic GABABRs inhibit neurotransmitter release by down regulat SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Rat Form Antigen/blocking Peptide Antigen 24-aa peptide rat GBR2 Designated (GBR22-P or control peptide/blocking peptide) conjugated to KLH, epitope location ~ C-terminus, Cytoplasmic SpCrossreactivity Rat GBR22-P control peptide is 100% conserved in mouse, canine, chimpanzee and human, 91% in chicken GBR2/GB2 or GABABR2 or GPR51/HG20. No significant homology is detected with GBR1 or other receptors. Antibody cross-reactivity in various species has not been studied. For research use only, not for diagnostic or therapeutic use.