Alpha Diagnostic International, Inc. Anti-Rat GABAb-R1b (GBR1b) Antiserum #1 GBR1B11-S

Anti-Rat GABAb-R1b (GBR1b) Antiserum #1 General Information GABA ( -amino butyric acid) is the most abundant neurotransmitter in mammalian brain. GABA exerts its effects through ionotropic ligand-gated GABAA, GABAC and GABAB receptors (GABABRs). Presynaptic GABABRs inhibit neurotransmitter release by down regulat SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Rat SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Antiserum Unpurified SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 16-aa peptide of rat GBR1b Designated (GBR1B11-P or control peptide) conjugated to KLH; Epitope location ~N-terminus, Extracellular domain SpCrossreactivity The 16 AA rat GBR1B11-P control peptide is 100% conserved in mouse and 93% conserved in human GBR1b. It is 100% conserved in various alternatively spliced rat GBR1b (844 aa), GBR1c (875 aa), and GBR1d (812 aa). No significant sequence homology is detected with GBR1a or GBR2 or other GABA receptors. Antibody cross-reactivity in various species has not been studied. For research use only, not for diagnostic or therapeutic use.