Alpha Diagnostic International, Inc. Rat Glutamic acid decarboxylase (GAD67) Control/blocking peptide # 1 GAD67-P

Rat Glutamic acid decarboxylase (GAD67) Control/blocking peptide # 1 General Information GAD; L-glutamate 1-carboxy-lyase, EC 4.1.115). In the CNS GAB is entirely restricted to GABAergic neurons. GAD is also present in the b-cells of the pancreas and autoantibodies to various GAD polypeptides are detected in insulin-dependent diabetes mellitu SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Rat Form Antigen/blocking Peptide Antigen 18-aa peptide from rat/mouse GAD67 (1); Designation (GAD67-P, control peptide) epitope location ~ N-terminus SpCrossreactivity The 18 AA rat GAD67 peptide sequences 100% conserved in mouse, 88% conserved in human and 61% in monkey GAD67. Antibody cross-reactivity in various species has not been studied. For research use only, not for diagnostic or therapeutic use.