Alpha Diagnostic International, Inc. Anti-Mouse Telomerase/EST2 antiserum # 3 EST23-S

Anti-Mouse Telomerase/EST2 antiserum # 3 General Information Purification of telomerase from the ciliate also revealed two protein of 43 and 123 kDa. p123 is a homolog of yeast Est2 (Essential for Telomerase activity). Mammalian homologs of yeast Est2 (also known as TP2 for Telomerase associated Protein 2; hEST2 SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Mouse SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Antiserum Unpurified SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 15-aa peptide of mouse EST2 ; Designated (EST23-P or control peptide). epitope location ~ Mid-region SpCrossreactivity The 15 AA mouse EST23-P control peptide sequence is 100% conserved in rat and human (1). No significant sequence homology is seen with yeast telomerase. We recommend the use of EST24 for the detection of yeast enzyme. Control peptide is recommended for antibody blocking studies to confirm specificity of antibodies. Actual cross-reactivity of antibodies in various species has not been studied For research use only, not for diagnostic or therapeutic use.