Alpha Diagnostic International, Inc. Human Prostaglandin E receptor 4 (EP4) control (blocking) peptide # 2 EP42-P

Human Prostaglandin E receptor 4 (EP4) control (blocking) peptide # 2 General Information EP4 (mouse 513 aa, rat 488 aa; human 488 aa, chromosome 5p13.1, ~ 90% interspecies homology) is expressed in intestine, lung, thymus, kidney, uterus, pancreas, spleen, heart, stomach, and brain. EP4 knockout mice show patent ductus arteriosus, and decrea SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Human Form Antigen/blocking Peptide Antigen 18-aa peptide of Human EP4; Designated (EP42-P or control peptide) conjugated to KLH; Epitope location~ C-terminal, Cytoplasmic domain SpCrossreactivity The human EP42-P control peptide is 100% conserved in rabbit, monkey, Bovine, and 94% in rat, canine and mouse EP4. No significant homology of EP42-P exist with other EP (1, 2 or 3) receptors. Antibody cross-reactivity in various species is not established For research use only, not for diagnostic or therapeutic use.