Alpha Diagnostic International, Inc. Human Prostaglandin E receptor 3 (EP3) control (blocking) peptide #2 EP32-P

Human Prostaglandin E receptor 3 (EP3) control (blocking) peptide #2 General Information EP3 (mouse 3-4 isoforms, 365-425 aa; rat 2 isoforms 364-365 aa; human 3-6 isoforms, 365-425 aa, chromosome 1p31.2,) is expressed in the kidney, brain, stomach, uterus, liver, skeletal muscle, intestine, and thymus. Alternative splicing of EP3 produces va SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Human Form Antigen/blocking Peptide Antigen 16-aa peptide of human EP3; Designated (EP32-P or control peptide /blocking peptide) conjugated to KLH; epitope location ~ N-terminus, Extracellular domain SpCrossreactivity The human EP32-P control peptide is located before the splicing point, therefore, it is conserved in all EP3 isoforms that differ at the C-terminus. It is 86% conserved in bovine, 87% in rabbit and ovine, 81% in pig, 68% in rat and mouse EP3. No significant homology of EP32-P exist with either mouse or rat EP3 or other EP (1, 2 or 4) receptors. Antibody cross-reactivity in various species is not established For research use only, not for diagnostic or therapeutic use.