Alpha Diagnostic International, Inc. Anti-Human Prostaglandin E receptor 3 (EP3) IgG #2, aff pure EP32-A

Anti-Human Prostaglandin E receptor 3 (EP3) IgG #2, aff pure General Information EP3 (mouse 3-4 isoforms, 365-425 aa; rat 2 isoforms 364-365 aa; human 3-6 isoforms, 365-425 aa, chromosome 1p31.2,) is expressed in the kidney, brain, stomach, uterus, liver, skeletal muscle, intestine, and thymus. Alternative splicing of EP3 produces va SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Human SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Affinity purified IgG SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 16-aa peptide of human EP3; Designated (EP32-P or control peptide /blocking peptide) conjugated to KLH; epitope location ~ N-terminus, Extracellular domain SpCrossreactivity The human EP32-P control peptide is located before the splicing point, therefore, it is conserved in all EP3 isoforms that differ at the C-terminus. It is 86% conserved in bovine, 87% in rabbit and ovine, 81% in pig, 68% in rat and mouse EP3. No significant homology of EP32-P exist with either mouse or rat EP3 or other EP (1, 2 or 4) receptors. Antibody cross-reactivity in various species is not established For research use only, not for diagnostic or therapeutic use.